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Laser: Laser beams will be applied to the zone where treatment is required

People taking heartburn medication, such as proton pump inhibitors, are at a higher risk for B12 deficiency and may benefit from alternative therapies to control/eliminate the heartburn or have regular Nutrient IV therapies and/or Vitamin B12 injections Elderly Vegans Vegetarians People with tapeworms Alcoholics Excessive use of antibiotics Excessive use of anti-convulsant medication Daily consumption of Aspirin may increase the risk for vitamin B12 deficiency

Rivaroxaban shares the CYP3A4/P-gp metabolism pathway with apixaban and would carry similar theoretical pharmacokinetic concerns